Peter B. Moore, Yale University, "How Should We Think About the Ribosome in 2012?"
Mar 27 2012, 11:00 am
Distinguished Lecture Series Guest Speaker:
Peter B. Moore
Sterling Professor Emeritus
Department of Chemistry
Date & Time:Tuesday, March 27, 2012, 11:00AM
Enormous progress has been made over the last decade in understanding the conformations adopted by the ribosome as it engages in protein synthesis, and important insights have been gained into the mechanism of that process. Today, it is all too easy to think of these structures as frames in a movie taken of a moving machine, and to explain the behavior of the ribosome in mechanical terms. Our current understanding of how these particles work will be outlined, and the case made for an alternative view of how the ribosome (and other “molecular machines”) actually work.