Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors

TitleInsights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors
Publication TypeJournal Article
Year of Publication2015
AuthorsSrinivasan, B, Skolnick J
JournalFEBS Journal
Volume282
Pagination1922 - 1938
Date Published05/2015
PDFhttp://cssb.biology.gatech.edu/skolnick/publications/pdffiles/351.pdf
10.1111/febs.13244
Short TitleFEBS J
Citekey351