
Currently I am using molecular tools in an attempt to understand the molecular biology of ovarian cancer, particularly the microenvironment of the cancerous cells. Instead of using bulk tumor tissue that is a heterogeneous collection of cells, I use laser capture microdissection to dissect only the cells of interest (i.e., only cancer cells or only stromal cells).
| Walker, D. and J.C. Avise. 1998. Principles of phylogeography as illustrated by freshwater and terrestrial turtles in the southeastern United States. Annual Review of Ecology and Systematics 29:23-58. |
| Avise, J.C. and D. Walker. 1999. Species realities and numbers in sexual vertebrates: Perspectives from an asexually transmitted genome. Proc. Natl. Acad. Sci. USA 96:992-995. |
| Avise, J.C. and D. Walker. 2000. Abandon all species concepts? A response. Conservation Genetics1:77-80. |
| Walker, D, B. Porter and J.C. Avise. 2002. Genetic parentage assessment in the crayfish Oronectes placidus, a high-fecundity invertebrate with extended maternal brood care. Mol Ecol. 11:2115-2122. |
| Avise, J.C., A.G. Jones, D. Walker, J.A. DeWoody, et al. 2002. Genetic mating systems and reproductive natural histories of fishes: lessons for ecology and evolution. Annu. Rev. of Gen 36:19-45. |
| Avise, J.C., A.J. Power and D. Walker. 2004. Genetic sex determination, gender identification, and pseudohermaphroditism in the Knobbed whelk, Busycon carica (Mollusca; Melongenidae) Proc. Roy. Soc. Lond. B 271:641-646. |
| Walker, D, A.J. Power and J.C. Avise. 2006. Paternity analysis based on sex-linked and autosomal microsatellite markers: a novel genetic approach, illustrated for an embryo-brooding marine gastropod. Submitted |