Dr. King Jordan
Associate Professor
School of Biology
Dr. King Jordan
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Contact information:
- School of Biology
- 310 Ferst Drive
- Cherry Emerson, Room 215
- Atlanta, GA 30332, Mail Code: 0230
- Tel: 404-385-2224
- Fax: 404-894-0519
- Email:
Research Interests
My research program is focused on understanding the genome level determinants of the diversification between evolutionary lineages. The approach that I use towards this end is computationally based and consists of the comparative analysis of large-scale genomic sequence, expression and functional data sets. This approach is facilitated by the accumulation of genome-scale data sets and the continuing development of the computational applications and infrastructure needed to employ such data. Ultimately, I hope to integrate our understanding of how evolutionary forces play out at distinct levels of biological organization.
More specifically, I am interested in understanding the nature of evolutionary innovations that have led to the emergence of complexity in eukaryotic lineages. I currently explore three distinct research areas relating to the evolution of eukaryotic genome complexity: i-the contributions of transposable elements to host gene regulatory and protein coding sequences, ii-the tempo and mode of gene regulatory and expression divergence and iii-convergent evolution of gene function.
Selected Publications
| Mariño-Ramírez, L. and I.K. Jordan, 2006. Transposable element derived DNaseI-hypersensitive sites in the human genome. Biol. Direct. 1:20 |
| Jordan, I.K, 2006. Evolutionary tinkering with transposable elements. Proc. Natl. Acad. Sci. USA 103:7941-7942 |
| Mariño-Ramírez, L., Lewis, K.C., Landsman, D. and I.K. Jordan, 2005. Transposable elements donate lineage-specific regulatory elements to host genomes. Cytogenet. Genome Res. 110: 333-341 |
| Jordan, I.K., Mariño-Ramírez, L. and E.V. Koonin, 2005. Evolutionary significance of gene expression divergence. Gene 345: 119-126 |
| Jordan, I.K., Kondrashov F.A., Adzhubei I.A., Wolf Y.I., Koonin E.V., Kondrashov A.S. and S. Sunyaev, 2005. A universal trend of amino acid gain and loss in protein evolution. Nature 433: 633-638 |
| Jordan, I.K., Mariño-Ramírez, L., W olf, Y.I. and E.V. Koonin, 2004. Conservation and co-evolution in the scale-free human gene coexpression network. Mol. Biol. Evol. 21: 2058-2070 |
| Jordan, I.K., Rogozin I.B., Glazko G.V. and E.V. Koonin, 2003. Origin of a substantial fraction of human regulatory sequences from transposable elements. Trends Genet. 19: 68-72 |