Michael Snyder
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Lewis B. Cullman Professor, Department of Molecular, Cellular and Developmental Biology |
Michael Snyder |
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Abstract: A variety of approaches have been used to integrate the functional elements of genomes of yeast and humans. Tiling arrays have been used to map new transcribed regions and transcriptional regulatory elements. This information has been used to construct regulatory networks and identify key components in networks. We have also examined network evolution in related yeasts. In addition, we have constructed and used proteome chips in yeast and humans to probe for novel biochemical activities, protein modification and human disease. Integration of diverse data types reveals common regulatory modules used by eukaryotes.
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