FINDSITE: ligand-binding site prediction from protein threading

Supporting Information for the work presented in Brylinski M, Skolnick J. (2008) A threading-based method (FINDSITE) for ligand-binding site prediction and functional annotation. Proc Natl Acad Sci U S A 105, 129-34. [Abstract]

Datasets:

• FINDSITE benchmark set

Function annotation:

• FINDSITE annotations
• GO statistics

Supporting Information for the work presented in Brylinski M, Skolnick J. (2009) Comparison of structure- and threading-based approaches to protein functional annotation. Proteins, submitted.

Structure-based approach:

• Binding pockets
• Molecular function
• Virtual screening

Threading-based approach (FINDSITE):

• Binding pockets
• Molecular function
• Virtual screening