Structure modeling of 907 G protein-coupled receptors in The Human genome


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Modeling results of TASSER for all 907 G protein-coupled receptors (GPCRs) in human genome. All sequences were collected from the GPCR database http://www.gpcr.org/7tm/ and http://www.expasy.org/cgi-bin/lists?7tmrlist.txt.

Reference: Zhang Y, Devries ME, Skolnick J. Structure Modeling of All Identified G Protein-Coupled Receptors in the Human Genome. PLoS Comput Biol. 2006 Feb 17;2(2):e13 PDF

Note: Commercial users may have access to the set of GPCR models after completing the license agreement and sending it to skolnick@gatech.edu

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Summary of folding results:

  • ID --- SWISS-PROT Identifier of the proteins.
  • Length --- Number of residues in the sequence.
  • Sequence --- Amino acid sequence from http://www.gpcr.org/7tm/ and http://www.expasy.org/cgi-bin/lists?7tmrlist.txt.
  • Template --- Template identified by the threading program PROSPECTOR_3.
  • Models --- Top five models generated by TASSER.
  • C-score --- Confidence score of the predicted models. The higher the C-score is, the more likely it is that a correct model is generated.
  • N-helix --- Number of helices > 17 residues in the first (top ranked) model.
  • Topology --- Topology of the first model.
  • Transmembrane --- Transmembrane helix bundle.
  • Globular --- Globular protein conformation.


[Table I]
[Table II]
[Table III]

ID Length Sequence Template Models C-score N-helix Topology Description
O00155 360 O00155 O00155 O00155 2.3 7 Transmembrane Probable G protein-coupled receptor GPR25
O00254 374 O00254 O00254 O00254 -0.8 7 Transmembrane Proteinase activated receptor 3 (PAR-3)
O00270 319 O00270 O00270 O00270 2.3 7 Transmembrane Probable G protein-coupled receptor GPR31
O00325 402 O00325 O00325 O00325 2.0 7 Transmembrane Prostaglandin E2 subtype EP3
O00326 393 O00326 O00326 O00326 2.1 7 Transmembrane Prostaglandin E2 subtype EP3
O00398 339 O00398 O00398 O00398 2.2 7 Transmembrane Putative P2Y purinoceptor 10 (P2Y10) (P2Y-like receptor)
O00421 344 O00421 O00421 O00421 2.4 7 Transmembrane C-C Chemokine other
O00574 342 O00574 O00574 O00574 2.1 7 Transmembrane C-X-C chemokine receptor type 6 (CXC-R6) (CXCR-6) (G protein-coupled receptor bonzo)
O00590 384 O00590 O00590 O00590 1.9 7 Transmembrane Chemokine binding protein 2 (Chemokine-binding protein D6) (C-C chemokine receptor D6) (CCR-9) (CCR10)
O14581 309 O14581 O14581 O14581 1.6 7 Transmembrane Olfactory receptor 7A17
O14626 319 O14626 O14626 O14626 2.3 7 Transmembrane Probable G protein-coupled receptor 171 (G protein-coupled receptor H963)
O14718 337 O14718 O14718 O14718 2.8 7 Transmembrane Visual pigment-like receptor peropsin
O14804 337 O14804 O14804 O14804 2.2 7 Transmembrane Trace amine
O14842 300 O14842 O14842 O14842 1.9 7 Transmembrane Probable G protein-coupled receptor GPR40
O14843 346 O14843 O14843 O14843 2.2 7 Transmembrane Probable G protein-coupled receptor GPR41
O15218 404 O15218 O15218 O15218 2.2 7 Transmembrane Adrenomedullin (AM-R)
O15529 346 O15529 O15529 O15529 2.3 7 Transmembrane Probable G protein-coupled receptor GPR42
O15552 330 O15552 O15552 O15552 2.4 7 Transmembrane Probable G protein-coupled receptor GPR43
O43192 309 O43192 O43192 O43192 1.9 6 Transmembrane Vasopressin
O43193 412 O43193 O43193 O43193 0.5 7 Transmembrane Motilin
O43194 453 O43194 O43194 O43194 0.4 7 Transmembrane Probable G protein-coupled receptor GPR39
O43603 387 O43603 O43603 O43603 2.2 7 Transmembrane Galanin type 2 (GAL2-R) (GALR2)
O43613 425 O43613 O43613 O43613 1.4 7 Transmembrane Orexin type 1 (OX1R) (Hypocretin type 1)
O43614 444 O43614 O43614 O43614 1.2 7 Transmembrane Orexin type 2 (OX2R) (Hypocretin type 2)
O43749 312 O43749 O43749 O43749 1.6 7 Transmembrane Olfactory receptor 1F1 (Olfactory receptor 16-35) (OR16-35)
O43869 311 O43869 O43869 O43869 1.8 7 Transmembrane Olfactory receptor 2T1 (Olfactory receptor 1-25) (OR1-25)
O43898 376 O43898 O43898 O43898 1.5 7 Transmembrane GPR45 like
O60403 315 O60403 O60403 O60403 1.6 7 Transmembrane Olfactory receptor 10H2
O60404 316 O60404 O60404 O60404 1.7 7 Transmembrane Olfactory receptor 10H3
O60412 320 O60412 O60412 O60412 1.5 7 Transmembrane Olfactory receptor 7C2 (Olfactory receptor 19-18) (OR19-18)
O60431 355 O60431 O60431 O60431 -0.3 7 Transmembrane Olfactory receptor 1I1 (Olfactory receptor 19-20) (OR19-20)
O60451 455 O60451 O60451 O60451 -1.0 8 Transmembrane Alpha Adrenoceptors type 1
O60755 368 O60755 O60755 O60755 2.2 7 Transmembrane Galanin type 3 (GAL3-R) (GALR3)
O60883 481 O60883 O60883 O60883 -0.9 7 Transmembrane Endothelin B receptor-like protein-2 (ETBR-LP-2)
O75205 403 O75205 O75205 O75205 -1.5 0 Globular G protein-coupled receptor family C group 5 member B precursor (Retinoic acid induced gene 2 protein) (RAIG-2) (A-69G12.1)
O75228 407 O75228 O75228 O75228 1.7 7 Transmembrane Thromboxane
O75303 215 O75303 O75303 O75303 2.8 5 Transmembrane CC-chemokine receptor
O75307 356 O75307 O75307 O75307 2.3 7 Transmembrane C-C Chemokine other
O75388 356 O75388 O75388 O75388 2.3 7 Transmembrane Probable G protein-coupled receptor GPR32
O75963 407 O75963 O75963 O75963 1.7 7 Transmembrane Probable G protein-coupled receptor 161 (G-protein coupled receptor RE2)
O76000 313 O76000 O76000 O76000 1.6 7 Transmembrane Olfactory receptor 2B3 (Olfactory receptor 6-4) (OR6-4) (Hs6M1-1)
O76001 311 O76001 O76001 O76001 1.7 7 Transmembrane Olfactory receptor 2J3 (Olfactory receptor 6-6) (OR6-6) (Hs6M1-3)
O76002 312 O76002 O76002 O76002 1.7 7 Transmembrane Olfactory receptor 2J2 (Olfactory receptor 6-8) (OR6-8) (Hs6M1-6)
O76099 320 O76099 O76099 O76099 1.5 7 Transmembrane Olfactory receptor 7C1 (Olfactory receptor TPCR86)
O76100 309 O76100 O76100 O76100 1.6 7 Transmembrane Olfactory receptor 7A10 (OST027)
O95006 317 O95006 O95006 O95006 1.6 7 Transmembrane Olfactory receptor 2F2 (Olfactory receptor 7-1) (OR7-1)
O95007 311 O95007 O95007 O95007 1.7 7 Transmembrane Olfactory receptor 6B1 (Olfactory receptor 7-3) (OR7-3)
O95013 312 O95013 O95013 O95013 1.7 7 Transmembrane Olfactory receptor 4F3
O95047 310 O95047 O95047 O95047 1.6 7 Transmembrane Olfactory receptor 2A4
O95136 353 O95136 O95136 O95136 2.2 7 Transmembrane Sphingosine 1-phosphate receptor Edg-5 (S1P receptor Edg-5)
O95221 314 O95221 O95221 O95221 1.7 7 Transmembrane Olfactory receptor 5F1 (Olfactory receptor 11-10) (OR11-10)
O95222 327 O95222 O95222 O95222 1.6 7 Transmembrane Olfactory receptor 6A2 (Olfactory receptor 11-55) (OR11-55)
O95357 357 O95357 O95357 O95357 -1.5 0 Globular Retinoic acid induced 3 protein (G protein-coupled receptor family C group 5 member A) (Retinoic acid induced gene 1 protein) (RAIG-1)
O95371 312 O95371 O95371 O95371 1.6 7 Transmembrane Olfactory receptor 2C1 (OLFmf3)
O95499 314 O95499 O95499 O95499 1.7 7 Transmembrane Olfactory II fam 2 / MOR256-262,270-285
O95665 410 O95665 O95665 O95665 1.2 7 Transmembrane Neurotensin type 2 (NT-R-2)
O95918 312 O95918 O95918 O95918 1.6 7 Transmembrane Olfactory receptor 2H2 (Hs6M1-12)
O95977 384 O95977 O95977 O95977 2.1 7 Transmembrane Sphingosine 1-phosphate receptor Edg-6 (S1P receptor Edg-6) (Endothelial differentiation G-protein-coupled receptor 6)
P03999 348 P03999 P03999 P03999 3.0 7 Transmembrane Blue-sensitive opsin
P04000 364 P04000 P04000 P04000 2.9 7 Transmembrane Red-sensitive opsin
P04001 364 P04001 P04001 P04001 2.9 7 Transmembrane Green-sensitive opsin
P04201 325 P04201 P04201 P04201 2.2 7 Transmembrane Mas proto-oncogene
P06850 196 P06850 P06850 P06850 -1.3 1 Globular
P07550 413 P07550 P07550 P07550 1.4 7 Transmembrane Beta-2 adrenergic
P08100 348 P08100 P08100 P08100 3.0 7 Transmembrane Rhodopsin (Opsin 2)
P08172 466 P08172 P08172 P08172 -0.8 7 Transmembrane Muscarinic acetylcholine M2
P08173 479 P08173 P08173 P08173 -0.8 7 Transmembrane Muscarinic acetylcholine M4
P08588 477 P08588 P08588 P08588 0.4 7 Transmembrane Beta-1 adrenergic
P08908 422 P08908 P08908 P08908 -0.6 7 Transmembrane 5-hydroxytryptamine 1A (5-HT-1A)
P08913 450 P08913 P08913 P08913 -0.9 7 Transmembrane Alpha-2a adrenergic (Subtype C10)
P11229 460 P11229 P11229 P11229 -0.8 7 Transmembrane Muscarinic acetylcholine M1
P13945 408 P13945 P13945 P13945 1.5 7 Transmembrane Beta-3 adrenergic
P14416 443 P14416 P14416 P14416 -0.7 7 Transmembrane D(2) dopamine
P17152 192 P17152 P17152 P17152 -2.4 0 Globular Protein PM1
P18089 450 P18089 P18089 P18089 -1.2 7 Transmembrane Alpha-2b adrenergic (Subtype C2)
P18825 462 P18825 P18825 P18825 -1.1 8 Transmembrane Alpha-2c adrenergic (Subtype C4)
P21452 398 P21452 P21452 P21452 2.4 7 Transmembrane Substance-K (SKR) (Neurokinin A) (NK-2R)
P21453 381 P21453 P21453 P21453 2.1 7 Transmembrane Sphingosine 1-phosphate receptor Edg-1
P21462 350 P21462 P21462 P21462 2.3 7 Transmembrane fMet-Leu-Phe (fMLP-R) (N-formyl peptide) (FPR)
P21554 472 P21554 P21554 P21554 -1.5 7 Transmembrane Cannabinoid 1 (CB1) (CB-R)
P21728 446 P21728 P21728 P21728 1.4 7 Transmembrane D(1A) dopamine
P21730 350 P21730 P21730 P21730 2.3 7 Transmembrane C5a anaphylatoxin chemotactic (C5a-R) (CD88)
P21731 369 P21731 P21731 P21731 2.0 7 Transmembrane Thromboxane A2 (TXA2-R) (Prostanoid TP)
P21917 467 P21917 P21917 P21917 -1.2 7 Transmembrane D(4) dopamine (D(2C) dopamine)
P21918 477 P21918 P21918 P21918 -0.9 7 Transmembrane D(1B) dopamine (D(5) dopamine)
P24530 442 P24530 P24530 P24530 -0.9 7 Transmembrane Endothelin B (ET-B) (Endothelin non-selective type)
P25021 359 P25021 P25021 P25021 2.0 7 Transmembrane Histamine H2 (Gastric receptor I)
P25024 350 P25024 P25024 P25024 2.1 7 Transmembrane High affinity interleukin-8 A (IL-8R A) (CXCR-1) (CDw128a)
P25025 360 P25025 P25025 P25025 2.3 7 Transmembrane High affinity interleukin-8 B (IL-8R B) (CXCR-2)
P25089 353 P25089 P25089 P25089 2.3 7 Transmembrane FMLP-related II (FMLP-R-II)
P25090 351 P25090 P25090 P25090 2.2 7 Transmembrane FMLP-related I (FMLP-R-I) (Lipoxin A4)
P25101 427 P25101 P25101 P25101 -0.6 7 Transmembrane Endothelin-1 (ET-A)
P25103 407 P25103 P25103 P25103 -0.5 7 Transmembrane Substance-P (SPR) (NK-1R)
P25105 342 P25105 P25105 P25105 2.1 7 Transmembrane Platelet activating factor (PAF-R)
P25106 362 P25106 P25106 P25106 2.3 7 Transmembrane G protein-coupled receptor RDC1 homolog (Chemokine orphan receptor 1)
P25116 425 P25116 P25116 P25116 -1.0 7 Transmembrane Proteinase activated receptor 1 (PAR-1) (Thrombin)
P25929 384 P25929 P25929 P25929 1.9 7 Transmembrane Neuropeptide Y type 1 (NPY1-R)
P28221 377 P28221 P28221 P28221 1.0 7 Transmembrane 5-hydroxytryptamine 1D (5-HT-1D) (5-HT-1D-alpha)
P28222 390 P28222 P28222 P28222 1.0 7 Transmembrane 5-hydroxytryptamine 1B (5-HT-1B) (5-HT-1D-beta) (S12)
P28223 471 P28223 P28223 P28223 1.1 7 Transmembrane 5-hydroxytryptamine 2A (5-HT-2A)
P28335 458 P28335 P28335 P28335 -0.5 7 Transmembrane 5-hydroxytryptamine 2C (5-HT-2C) (5-HT-1C)
P28336 390 P28336 P28336 P28336 2.3 7 Transmembrane Neuromedin-B (NMB-R) (Neuromedin-B-preferring bombesin)
P28566 365 P28566 P28566 P28566 0.7 7 Transmembrane 5-hydroxytryptamine 1E (5-HT-1E) (S31)
P29274 412 P29274 P29274 P29274 1.7 7 Transmembrane Adenosine A2A
P29275 332 P29275 P29275 P29275 1.8 7 Transmembrane Adenosine A2B
P29371 465 P29371 P29371 P29371 2.1 7 Transmembrane Neuromedin K (NKR) (Neurokinin B) (NK-3R)
P30411 391 P30411 P30411 P30411 1.5 7 Transmembrane B2 bradykinin (BK-2R) (B2R)
P30518 371 P30518 P30518 P30518 2.1 7 Transmembrane Vasopressin V2 (Renal-type arginine vasopressin) (AVPR V2)
P30542 326 P30542 P30542 P30542 1.8 7 Transmembrane Adenosine A1
P30550 384 P30550 P30550 P30550 2.3 7 Transmembrane Gastrin-releasing peptide (GRP-R) (GRP-preferring bombesin)
P30556 359 P30556 P30556 P30556 2.1 7 Transmembrane Type-1 angiotensin II (AT1)
P30559 389 P30559 P30559 P30559 1.8 7 Transmembrane Oxytocin (OTR)
P30872 391 P30872 P30872 P30872 2.3 7 Transmembrane Somatostatin type 1 (SS1R) (SRIF-2)
P30874 369 P30874 P30874 P30874 2.5 7 Transmembrane Somatostatin type 2 (SS2R) (SRIF-1)
P30939 366 P30939 P30939 P30939 0.6 8 Transmembrane 5-hydroxytryptamine 1F (5-HT-1F)
P30953 314 P30953 P30953 P30953 1.6 7 Transmembrane Olfactory receptor 1E1 (Olfactory receptor-like protein HGMP07I) (Olfactory receptor 17-2/17-32) (OR17-2) (OR17-32)
P30954 320 P30954 P30954 P30954 1.8 7 Transmembrane Olfactory receptor 10J1 (Olfactory receptor-like protein HGMP07J)
P30968 328 P30968 P30968 P30968 2.1 7 Transmembrane Gonadotropin-releasing hormone (GnRH receptor) (GnRH-R)
P30988 490 P30988 P30988 P30988 -0.6 1 Globular Calcitonin (CT-R)
P30989 418 P30989 P30989 P30989 1.6 7 Transmembrane Neurotensin type 1 (NT-R-1)
P30991 352 P30991 P30991 P30991 2.3 7 Transmembrane
P31391 388 P31391 P31391 P31391 2.3 7 Transmembrane Somatostatin type 4 (SS4R)
P32238 428 P32238 P32238 P32238 0.7 7 Transmembrane Cholecystokinin type A (CCK-A-R)
P32239 447 P32239 P32239 P32239 0.8 7 Transmembrane Gastrin/cholecystokinin type B (CCK-B-R)
P32241 457 P32241 P32241 P32241 -0.7 2 Globular Vasoactive intestinal polypeptide 1 (VIP-R-1)
P32245 332 P32245 P32245 P32245 1.8 7 Transmembrane Melanocortin-4 (MC4-R)
P32246 355 P32246 P32246 P32246 2.3 7 Transmembrane C-C chemokine receptor type 1 (C-C CKR-1) (CCR-1)
P32247 399 P32247 P32247 P32247 2.1 7 Transmembrane Bombesin subtype-3 (BRS-3)
P32248 378 P32248 P32248 P32248 0.8 7 Transmembrane C-C chemokine receptor type 7 (C-C CKR-7) (CCR-7) (EBV-induced G protein-coupled receptor 1) (EBI1) (BLR2)
P32249 361 P32249 P32249 P32249 2.2 7 Transmembrane EBV-induced G protein-coupled receptor 2 (EBI2)
P32302 372 P32302 P32302 P32302 2.4 7 Transmembrane C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitts lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR15)
P32745 418 P32745 P32745 P32745 2.0 7 Transmembrane Somatostatin type 3 (SS3R)
P33032 325 P33032 P33032 P33032 1.9 7 Transmembrane Melanocortin-5 (MC5-R) (MC-2)
P33765 318 P33765 P33765 P33765 2.4 7 Transmembrane Adenosine A3
P34969 479 P34969 P34969 P34969 -1.2 7 Transmembrane 5-hydroxytryptamine 7 (5-HT-7) (5-HT-X)
P34972 360 P34972 P34972 P34972 2.0 7 Transmembrane Cannabinoid 2 (CB2) (CX5)
P34981 398 P34981 P34981 P34981 1.8 7 Transmembrane Thyrotropin-releasing hormone (TRH-R)
P34982 312 P34982 P34982 P34982 1.6 7 Transmembrane Olfactory receptor 1D2 (Olfactory receptor-like protein HGMP07E) (Olfactory receptor 17-4) (OR17-4)
P34995 402 P34995 P34995 P34995 1.1 7 Transmembrane Prostaglandin E2, EP1 subtype (Prostanoid EP1)
P34998 444 P34998 P34998 P34998 -1.1 1 Globular Corticotropin releasing factor 1 (CRF1)
P35346 364 P35346 P35346 P35346 2.5 7 Transmembrane Somatostatin type 5 (SS5R)
P35348 466 P35348 P35348 P35348 0.8 7 Transmembrane Alpha-1a adrenergic (Alpha-1C)
P35367 487 P35367 P35367 P35367 -1.7 8 Transmembrane Histamine H1
P35372 400 P35372 P35372 P35372 2.1 7 Transmembrane Mu-type opioid (MOR-1)
P35408 488 P35408 P35408 P35408 -0.9 7 Transmembrane Prostaglandin E2, EP4 subtype (Prostanoid EP4)
P35410 378 P35410 P35410 P35410 0.8 7 Transmembrane Mas-related MRG (MAS-R) (MAS1-like)
P35414 380 P35414 P35414 P35414 2.2 7 Transmembrane Apelin receptor (G protein-coupled receptor APJ) (Angiotensin receptor-like 1) (HG11)
P35462 400 P35462 P35462 P35462 -0.2 7 Transmembrane D(3) dopamine
P37288 418 P37288 P37288 P37288 1.8 7 Transmembrane Vasopressin V1A (Vascular/hepatic-type arginine vasopressin) (AVPR V1A)
P41143 372 P41143 P41143 P41143 2.4 7 Transmembrane Delta-type opioid (DOR-1)
P41145 380 P41145 P41145 P41145 2.5 7 Transmembrane Kappa-type opioid (KOR-1)
P41146 370 P41146 P41146 P41146 2.5 7 Transmembrane Nociceptin (Orphanin FQ) (Kappa-type 3 opioid) (KOR-3)
P41231 377 P41231 P41231 P41231 2.4 7 Transmembrane P2Y purinoceptor 2 (P2Y2) (P2U purinoceptor 1) (P2U1) (ATP receptor)
P41586 468 P41586 P41586 P41586 -0.3 0 Globular Pituitary adenylate cyclase activating polypeptide type I
P41587 438 P41587 P41587 P41587 -1.0 0 Globular Vasoactive intestinal polypeptide 2 (VIP-R-2) (PACAP-R-3)
P41595 481 P41595 P41595 P41595 -0.9 7 Transmembrane 5-hydroxytryptamine 2B (5-HT-2B)
P41597 374 P41597 P41597 P41597 2.2 7 Transmembrane C-C chemokine receptor type 2 (C-C CKR-2) (CCR-2) (MCP-1-R)
P41968 360 P41968 P41968 P41968 -0.2 7 Transmembrane Melanocortin-3 (MC3-R)
P43088 359 P43088 P43088 P43088 1.9 7 Transmembrane Prostaglandin F2-alpha (Prostanoid FP)
P43115 390 P43115 P43115 P43115 2.2 7 Transmembrane Prostaglandin E2, EP3 subtype (Prostanoid EP3)
P43116 358 P43116 P43116 P43116 1.7 7 Transmembrane Prostaglandin E2, EP2 subtype (Prostanoid EP2)
P43119 386 P43119 P43119 P43119 2.2 7 Transmembrane Prostacyclin (Prostanoid IP)
P43220 463 P43220 P43220 P43220 -1.0 6 Transmembrane Glucagon-like peptide 1 (GLP-1-R)
P43657 344 P43657 P43657 P43657 1.8 7 Transmembrane P2Y purinoceptor 5 (P2Y5) (RB intron encoded)
P46089 330 P46089 P46089 P46089 2.2 7 Transmembrane Probable G protein-coupled receptor GPR3
P46091 355 P46091 P46091 P46091 2.1 7 Transmembrane Probable G protein-coupled receptor GPR1
P46092 362 P46092 P46092 P46092 2.4 7 Transmembrane C-C chemokine receptor type 10 (C-C CKR-10) (CCR-10)
P46093 362 P46093 P46093 P46093 2.3 8 Transmembrane Probable G protein-coupled receptor GPR4 (GPR19)
P46094 333 P46094 P46094 P46094 1.9 7 Transmembrane Chemokine XC receptor 1 (XC chemokine receptor 1) (Lymphotactin receptor)
P46095 362 P46095 P46095 P46095 2.2 7 Transmembrane Probable G protein-coupled receptor GPR6
P46663 353 P46663 P46663 P46663 2.3 7 Transmembrane B1 bradykinin (BK-1R) (B1R)
P47211 349 P47211 P47211 P47211 2.4 7 Transmembrane Galanin type 1 (GAL1-R) (GALR1)
P47775 334 P47775 P47775 P47775 2.1 7 Transmembrane Probable G protein-coupled receptor 12
P47804 291 P47804 P47804 P47804 2.8 7 Transmembrane RPE-retinal G protein-coupled receptor
P47871 477 P47871 P47871 P47871 -0.6 3 Globular Glucagon (GL-R)
P47872 440 P47872 P47872 P47872 -1.0 2 Globular Secretin (SCT-R)
P47881 315 P47881 P47881 P47881 1.7 7 Transmembrane Olfactory receptor 3A1 (Olfactory receptor 17-40) (OR17-40)
P47883 348 P47883 P47883 P47883 1.4 7 Transmembrane Olfactory receptor 3A4 (Olfactory receptor 17-24) (OR17-24)
P47884 311 P47884 P47884 P47884 1.7 7 Transmembrane Olfactory receptor 1D4 (Olfactory receptor 17-30) (OR17-30)
P47887 323 P47887 P47887 P47887 1.5 7 Transmembrane Olfactory receptor 1E2 (Olfactory receptor 17-93/17-135/17-136) (OR17-93) (OR17-135) (OR17-136)
P47888 315 P47888 P47888 P47888 1.7 7 Transmembrane Olfactory receptor 3A3 (Olfactory receptor 17-201) (OR17-201)
P47890 313 P47890 P47890 P47890 1.6 7 Transmembrane Olfactory receptor 1G1 (Olfactory receptor 17-209) (OR17-209)
P47893 315 P47893 P47893 P47893 1.8 7 Transmembrane Olfactory receptor 3A2 (Olfactory receptor 17-228) (OR17-228)
P47898 357 P47898 P47898 P47898 1.7 7 Transmembrane 5-hydroxytryptamine 5A (5-HT-5A)
P47900 373 P47900 P47900 P47900 2.3 7 Transmembrane P2Y purinoceptor 1 (ATP receptor) (P2Y1)
P47901 424 P47901 P47901 P47901 1.4 7 Transmembrane Vasopressin V1B (AVPR V1B) (Vasopressin V3) (AVPR V3)
P48039 350 P48039 P48039 P48039 2.3 7 Transmembrane Melatonin type 1A (Mel-1A-R)
P48145 328 P48145 P48145 P48145 2.6 7 Transmembrane Neuropeptides B/W receptor type 1 (G protein-coupled receptor 7)
P48146 333 P48146 P48146 P48146 2.4 7 Transmembrane Neuropeptides B/W receptor type 2 (G protein-coupled receptor 8)
P48546 466 P48546 P48546 P48546 -0.6 3 Globular Gastric inhibitory peptide (GIP-R)
P49019 387 P49019 P49019 P49019 -0.2 6 Transmembrane Probable G protein-coupled receptor GPR109B (G protein-coupled receptor HM74)
P49146 381 P49146 P49146 P49146 2.6 7 Transmembrane Neuropeptide Y type 2 (NPY2-R)
P49238 355 P49238 P49238 P49238 2.0 7 Transmembrane CX3C chemokine receptor 1 (C-X3-C CKR-1) (CX3CR1) (Fractalkine receptor) (V28) (CMK-BRL-1)
P49286 362 P49286 P49286 P49286 2.6 7 Transmembrane Melatonin type 1B (Mel-1B-R)
P49682 368 P49682 P49682 P49682 1.3 7 Transmembrane C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3)
P49683 370 P49683 P49683 P49683 2.2 7 Transmembrane Probable G protein-coupled receptor GPR10
P49685 360 P49685 P49685 P49685 1.7 7 Transmembrane Probable G protein-coupled receptor GPR15
P50052 363 P50052 P50052 P50052 2.6 7 Transmembrane Type-2 angiotensin II (AT2)
P50391 375 P50391 P50391 P50391 1.9 7 Transmembrane Neuropeptide Y type 4 (NPY4-R)
P50406 440 P50406 P50406 P50406 1.1 7 Transmembrane 5-hydroxytryptamine 6 (5-HT-6)
P51582 365 P51582 P51582 P51582 2.5 7 Transmembrane P2Y purinoceptor 4 (P2Y4) (Uridine nucleotide) (UNR) (P2P)
P51677 355 P51677 P51677 P51677 2.3 7 Transmembrane C-C chemokine receptor type 3 (C-C CKR-3) (CCR-3)
P51679 360 P51679 P51679 P51679 2.3 7 Transmembrane C-C chemokine receptor type 4 (C-C CKR-4) (CCR-4)
P51681 352 P51681 P51681 P51681 2.0 7 Transmembrane C-C chemokine receptor type 5 (C-C CKR-5) (CCR-5)
P51684 374 P51684 P51684 P51684 2.3 7 Transmembrane C-C chemokine receptor type 6 (C-C CKR-6) (CCR-6) (GPR-CY4) (GPRCY4) (Chemokine receptor-like 3) (CKR-L3)
P51685 355 P51685 P51685 P51685 2.0 7 Transmembrane C-C chemokine receptor type 8 (C-C CKR-8) (CCR-8) (GPR-CY6) (GPRCY6) (Chemokine receptor-like 1) (CKR-L1) (TER1)
P51686 357 P51686 P51686 P51686 2.2 7 Transmembrane C-C chemokine receptor type 9 (C-C CKR-9) (CCR-9) (GPR-9-6)
P51810 404 P51810 P51810 P51810 -2.1 1 Globular Ocular albinism proteins
P55085 397 P55085 P55085 P55085 -0.7 8 Transmembrane Proteinase activated receptor 2 (PAR-2)
P58170 312 P58170 P58170 P58170 1.7 7 Transmembrane Olfactory receptor 1D5 (Olfactory receptor 17-31) (OR17-31)
P58173 313 P58173 P58173 P58173 1.7 7 Transmembrane Olfactory receptor 2B6 (Olfactory receptor 6-31) (OR6-31) (Hs6M1-32)
P58180 307 P58180 P58180 P58180 1.7 7 Transmembrane Olfactory receptor 4D2
P58181 314 P58181 P58181 P58181 1.6 7 Transmembrane Olfactory receptor 10A3 (HTPCRX12)
P58182 307 P58182 P58182 P58182 1.7 7 Transmembrane Olfactory receptor 12D2 (Hs6M1-20)
P59922 312 P59922 P59922 P59922 1.7 7 Transmembrane Olfactory receptor 2B8 (Hs6M1-29P)
Q01718 297 Q01718 Q01718 Q01718 2.2 7 Transmembrane Adrenocorticotropic hormone (ACTH-R) (MC2-R)
Q01726 317 Q01726 Q01726 Q01726 1.8 7 Transmembrane Melanocyte stimulating hormone (MSH-R)
Q02643 423 Q02643 Q02643 Q02643 -0.9 0 Globular Growth hormone-releasing hormone (GRFR)
Q13167 399 Q13167 Q13167 Q13167 -0.3 7 Transmembrane Dopamine Vertebrate type 3
Q13258 359 Q13258 Q13258 Q13258 1.9 7 Transmembrane Prostaglandin D2 (Prostanoid DP)
Q13304 367 Q13304 Q13304 Q13304 2.3 7 Transmembrane Probable G protein-coupled receptor GPR17
Q13324 411 Q13324 Q13324 Q13324 -0.2 2 Globular Corticotropin releasing factor 2 (CRF2)
Q13606 314 Q13606 Q13606 Q13606 1.6 7 Transmembrane Olfactory receptor 5I1 (Olfactory receptor-like protein OLF1)
Q13607 317 Q13607 Q13607 Q13607 1.6 7 Transmembrane Olfactory receptor 2F1 (Olfactory receptor-like protein OLF3)
Q13639 388 Q13639 Q13639 Q13639 1.7 7 Transmembrane 5-hydroxytryptamine 4 (5-HT-4)
Q13675 499 Q13675 Q13675 Q13675 -1.0 7 Transmembrane Alpha Adrenoceptors type 1
Q13725 359 Q13725 Q13725 Q13725 2.5 7 Transmembrane Type-1B angiotensin II (AT1A)
Q13729 429 Q13729 Q13729 Q13729 0.9 7 Transmembrane Alpha Adrenoceptors type 1
Q14330 331 Q14330 Q14330 Q14330 2.2 7 Transmembrane Probable G protein-coupled receptor GPR18
Q14968 322 Q14968 Q14968 Q14968 1.7 5 Transmembrane Putative / unclassified Class A GPCRs
Q15062 316 Q15062 Q15062 Q15062 1.6 7 Transmembrane Olfactory receptor 2H3 (Olfactory receptor-like protein FAT11)
Q15077 328 Q15077 Q15077 Q15077 2.3 7 Transmembrane P2Y purinoceptor 6 (P2Y6)
Q15391 338 Q15391 Q15391 Q15391 2.5 7 Transmembrane P2Y purinoceptor 14 (P2Y14) (UDP-glucose receptor) (G protein-coupled receptor 105)
Q15612 314 Q15612 Q15612 Q15612 1.7 7 Transmembrane Olfactory receptor 1Q1 (Olfactory receptor TPCR106) (Olfactory receptor 9-A) (OR9-A) (OST226)
Q15615 310 Q15615 Q15615 Q15615 1.7 7 Transmembrane Olfactory receptor 4D1 (Olfactory receptor TPCR16)
Q15619 314 Q15619 Q15619 Q15619 1.6 7 Transmembrane Olfactory receptor 1C1 (Olfactory receptor TPCR27)
Q15620 311 Q15620 Q15620 Q15620 1.7 7 Transmembrane Olfactory receptor 8B8 (Olfactory receptor TPCR85) (Olfactory-like receptor JCG8)
Q15622 319 Q15622 Q15622 Q15622 1.5 7 Transmembrane Olfactory receptor 7A5 (Olfactory receptor TPCR92)
Q15722 352 Q15722 Q15722 Q15722 2.4 7 Transmembrane Leukotriene B4 1 (LTB4-R 1) (P2Y purinoceptor 7) (P2Y7) (Chemoattractant receptor-like 1)
Q15743 365 Q15743 Q15743 Q15743 2.6 7 Transmembrane Sphingosylphosphorylcholine receptor
Q15760 415 Q15760 Q15760 Q15760 2.1 7 Transmembrane Probable G protein-coupled receptor GPR19 (GPR-NGA)
Q15761 455 Q15761 Q15761 Q15761 -0.9 7 Transmembrane Neuropeptide Y type 5 (NPY5-R)
Q16144 447 Q16144 Q16144 Q16144 0.1 7 Transmembrane CCK type B
Q16432 187 Q16432 Q16432 Q16432 0.1 3 Transmembrane Endothelin-A receptor delta 4
Q16433 318 Q16433 Q16433 Q16433 0.2 6 Transmembrane Endothelin-A receptor delta 3-4
Q16503 253 Q16503 Q16503 Q16503 1.3 0 Globular Thyrotropin receptor-I
Q16570 336 Q16570 Q16570 Q16570 1.9 7 Transmembrane Duffy antigen/chemokine receptor (Fy glycoprotein) (GpFy) (Glycoprotein D)
Q16581 482 Q16581 Q16581 Q16581 -1.7 8 Transmembrane C3a anaphylatoxin chemotactic (C3a-R) (C3AR)
Q16602 461 Q16602 Q16602 Q16602 -0.7 0 Globular Calcitonin gene-related peptide type 1 (CGRP type 1)
Q7Z3S0 344 Q7Z3S0 Q7Z3S0 Q7Z3S0 2.0 7 Transmembrane Purinoceptor Other
Q7Z3S6 344 Q7Z3S6 Q7Z3S6 Q7Z3S6 2.5 7 Transmembrane Purinoceptor Other
Q7Z3T1 314 Q7Z3T1 Q7Z3T1 Q7Z3T1 1.7 7 Transmembrane Olfactory II fam 2 / MOR256-262,270-285
Q7Z3W3 376 Q7Z3W3 Q7Z3W3 Q7Z3W3 -1.0 7 Transmembrane Proteinase-activated
Q7Z5J9 300 Q7Z5J9 Q7Z5J9 Q7Z5J9 -2.4 6 Transmembrane G protein-coupled receptor family C group 5 member D
Q7Z5R9 397 Q7Z5R9 Q7Z5R9 Q7Z5R9 -0.8 7 Transmembrane Histamine type 2
Q7Z601 462 Q7Z601 Q7Z601 Q7Z601 -1.1 8 Transmembrane Putative / unclassified Class A GPCRs
Q7Z603 350 Q7Z603 Q7Z603 Q7Z603 2.8 7 Transmembrane Putative / unclassified Class A GPCRs
Q7Z604 494 Q7Z604 Q7Z604 Q7Z604 -0.5 7 Transmembrane Putative / unclassified Class A GPCRs
Q7Z605 376 Q7Z605 Q7Z605 Q7Z605 1.8 7 Transmembrane Putative / unclassified Class A GPCRs
Q7Z710 415 Q7Z710 Q7Z710 Q7Z710 1.9 7 Transmembrane C-X-C Chemokine type 3
Q7Z7I1 384 Q7Z7I1 Q7Z7I1 Q7Z7I1 1.4 7 Transmembrane C-C Chemokine type X
Q7Z7M2 393 Q7Z7M2 Q7Z7M2 Q7Z7M2 0.2 7 Transmembrane Putative / unclassified Class B GPCRs
Q86TH8 465 Q86TH8 Q86TH8 Q86TH8 -1.1 7 Transmembrane Alpha Adrenoceptors type 2
Q86U87 313 Q86U87 Q86U87 Q86U87 1.7 7 Transmembrane Putative / unclassified Class A GPCRs
Q86V16 327 Q86V16 Q86V16 Q86V16 2.5 7 Transmembrane Purinoceptor Other
Q86V80 314 Q86V80 Q86V80 Q86V80 2.2 6 Transmembrane Opioid type M
Q86VP7 481 Q86VP7 Q86VP7 Q86VP7 -1.1 7 Transmembrane Endothelin B receptor-like protein-2 precursor (ETBR-LP-2) (G protein- coupled receptor 37 like 1)
Q86VZ1 359 Q86VZ1 Q86VZ1 Q86VZ1 2.4 7 Transmembrane Putative / unclassified Class A GPCRs
Q86WP7 384 Q86WP7 Q86WP7 Q86WP7 2.2 7 Transmembrane Putative / unclassified Class A GPCRs
Q86YW1 317 Q86YW1 Q86YW1 Q86YW1 2.0 7 Transmembrane Melanocyte stimulating hormone
Q8IU63 238 Q8IU63 Q8IU63 Q8IU63 1.6 5 Transmembrane Olfactory receptor
Q8IUZ1 355 Q8IUZ1 Q8IUZ1 Q8IUZ1 2.5 7 Transmembrane Interleukin-8 type B
Q8IV06 319 Q8IV06 Q8IV06 Q8IV06 2.5 7 Transmembrane Putative / unclassified Class A GPCRs
Q8IV17 440 Q8IV17 Q8IV17 Q8IV17 -0.9 2 Globular Secretin
Q8IV19 337 Q8IV19 Q8IV19 Q8IV19 2.7 7 Transmembrane Cysteinyl leukotriene
Q8IWP3 366 Q8IWP3 Q8IWP3 Q8IWP3 2.4 7 Transmembrane Opioid type K
Q8IWW3 418 Q8IWW3 Q8IWW3 Q8IWW3 0.3 7 Transmembrane Opioid type M
Q8IWW4 446 Q8IWW4 Q8IWW4 Q8IWW4 -0.8 7 Transmembrane Opioid type M
Q8IX08 323 Q8IX08 Q8IX08 Q8IX08 1.4 5 Transmembrane Opsin 3 (Encephalopsin) (Panopsin)
Q8IXB0 341 Q8IXB0 Q8IXB0 Q8IXB0 2.2 7 Transmembrane Opioid type X
Q8IXD9 220 Q8IXD9 Q8IXD9 Q8IXD9 0.5 4 Transmembrane fragment
Q8IXE0 232 Q8IXE0 Q8IXE0 Q8IXE0 1.9 4 Transmembrane fragment
Q8IXE1 308 Q8IXE1 Q8IXE1 Q8IXE1 1.7 7 Transmembrane Olfactory receptor 4N5
Q8IXE2 328 Q8IXE2 Q8IXE2 Q8IXE2 2.0 7 Transmembrane Putative / unclassified Class A GPCRs
Q8IXE4 399 Q8IXE4 Q8IXE4 Q8IXE4 -2.0 7 Transmembrane Putative / unclassified Class B GPCRs
Q8IXE7 254 Q8IXE7 Q8IXE7 Q8IXE7 1.6 6 Transmembrane Olfactory II fam 5 / MOR172-224,249,254
Q8IXH9 388 Q8IXH9 Q8IXH9 Q8IXH9 1.7 7 Transmembrane Serotonin Vertebrate type 4
Q8IY58 384 Q8IY58 Q8IY58 Q8IY58 0.9 6 Transmembrane Neurotensin
Q8IYL9 337 Q8IYL9 Q8IYL9 Q8IYL9 2.3 7 Transmembrane Psychosine receptor (G protein-coupled receptor 65) (T cell-death associated protein 8)
Q8IYT7 338 Q8IYT7 Q8IYT7 Q8IYT7 2.6 7 Transmembrane Platelet ADP & KI01 receptors
Q8IZ08 482 Q8IZ08 Q8IZ08 Q8IZ08 0.6 7 Transmembrane Putative / unclassified Class A GPCRs
Q8N0W0 194 Q8N0W0 Q8N0W0 Q8N0W0 1.8 4 Transmembrane fragment
Q8N0W1 211 Q8N0W1 Q8N0W1 Q8N0W1 2.6 5 Transmembrane fragment
Q8N0X1 227 Q8N0X1 Q8N0X1 Q8N0X1 2.1 5 Transmembrane fragment
Q8N0Y1 304 Q8N0Y1 Q8N0Y1 Q8N0Y1 0.8 7 Transmembrane Olfactory II fam 8 / MOR161-171
Q8N0Y3 316 Q8N0Y3 Q8N0Y3 Q8N0Y3 1.7 7 Transmembrane Olfactory receptor 4N4
Q8N0Y5 310 Q8N0Y5 Q8N0Y5 Q8N0Y5 1.9 7 Transmembrane Olfactory receptor 8I2
Q8N0Z0 347 Q8N0Z0 Q8N0Z0 Q8N0Z0 -1.7 0 Globular fragment
Q8N127 324 Q8N127 Q8N127 Q8N127 1.6 7 Transmembrane Olfactory receptor 5AS1
Q8N146 312 Q8N146 Q8N146 Q8N146 1.8 7 Transmembrane Olfactory receptor 8H3
Q8N148 313 Q8N148 Q8N148 Q8N148 1.8 7 Transmembrane Olfactory receptor 6V1
Q8N162 312 Q8N162 Q8N162 Q8N162 1.7 7 Transmembrane Olfactory receptor 8H2

[Table I]
[Table II]
[Table III]