Georgia Institute of TechnologyCenter for the study of systems biology
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Dr. Ying Huang

Postdoctoral Fellow

Ying
Ying Huang

    Contact information:
  • Center for the Study of Systems Biology
  • Skolnick Lab
  • Tel:(404) 407-8971
  • Fax:(404) 385-7478
  • Email:yhuang31@mail.gatech.edu

Research Interests

    The complete of human genome project has promised a revolution in medicine. The genome encodes 20,000 to 25,000 genes; many of them may provide keys to treating diseases. Although many genomic and proteomic approaches have been developed to discover new drug targets (proteins involved in interactions with bioactive molecules), identification of novel drug targets is still time-consuming and expensive. Several bioinformatics methods for drug target prediction havebeen proposed. My research focus on using machine learning methods to prioritize proteins potential to be a drug target.

List of publications:

[1] Y. Huang and Y. Li. Prediction of protein subcellular locations using fuzzy k-NN method. Bioinformatics, 2004, 20: 21-28.
[2] Y. Huang, J. Cai, L. Ji and Y. Li. Classifying G-protein coupled receptors with bagging classification tree. Computational Biology and Chemistry, 2004, 28: 275-280.
[3] Y. Huang and Y. Li. Classifying G-protein Coupled Receptors with Support Vector Machine. Advances in Neural Networks - ISNN 2004, Springer LNCS, 2004, 3174: 448-452.
[4] J. Cai, J. Zhang, Y. Huang and Y. Li. ATD: a web-oriented database for collection of publicly alternative translational initiation events. Bioinformatics, 2005, 21: 4312-4314
[5] J. Cai, Y. Huang, F. Li and Y. Li. Alteration of protein subcellular location and domain formation by alternative translational initiation. Proteins, 2006 62: 793-799
[6] J. Cai, Y. Huang, L. Ji and Y. Li. Inferring protein-protein interactions from messenger RNA expression profiles with SVM. Journal of Biological Systems, 2005, 13: 287-298.
[7] Chinese Schizophrenia Consortium. Association study of an SNP combination pattern in the dopaminergic pathway in paranoid schizophrenia - A novel strategy for complex disorders. Molecular Psychiatry, 2004, 9: 510-521.
[8] Ma Fei, Zhuang Yonglong, Huang Ying, Li Yanda. Exploring Codon Usage Patterns of Alternatively Spliced Genes in Human Chromosome 1. Tsinghua Science andTechnology, 2004, 9: 98-107.
[9] LifeiHuang, Ying Huang and YandaLi. Utility max-min fairness and its application in ABR service. Journal of China Institute of Communications, 2001; 22(7): 10-17. (In Chinese)