DBD-Hunter: Prediction of DNA-binding Protein Function (Beta-release)

DNA-Binding Domain Hunter (DBD-Hunter) is a knowledge-based method for predicting DNA-binding proteins function from protein structure. The method combines structural comparison and evaluation of DNA-protein interaction energy, which is calculated use a statistical pair potential derived from crystal structures of DNA-protein complexes. Details of the method is described in the reference below. To use the webservice of this program, please upload a protein structure file in the PDB format. The results will be sent back to your through e-mail address you provided.

If you find the service useful, please cite the following publication:

M. Gao and J. Skolnick. 2008. DBD-Hunter: A knowledge-based method for the prediction of DNA-protein interactions. Nucleic Acids Research, 36(12): 3978-3992. PDF

SUBMIT YOUR STRUCTURE HERE